β-nicotinamide mononucleotide production in Vibrio natriegens: a preliminary study

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β-nicotinamide mononucleotide production in Vibrio natriegens: a preliminary study

Authors

Tran, L. H.; Tran, P. V. T.; Pham, D. H. T.; Nguyen, G. T.; Nghiem, T. T.; Pham, A. D.; Pham, N. Q.; Le, T. T.; Nguyen, L. N.; Dang, M. T. N.; Tran, T. H.; Tran, K. V.; Le, H. Q.

Abstract

Nicotinamide mononucleotide (NMN), is a promising nutraceutical attracting much attention for its pharmacological and anti-aging efficacies. However, NMN-containing commercial products are very high-priced due to the lack of efficient and facile methods for industrial-scale production. To date, various metabolic engineering strategies have been successfully applied to produce NMN in Escherichia coli. Recently, Vibrio natriegens has become a promising host in the bioindustry thanks to its rapid growth and capabilities of broad substrate utilization. This study aims to evaluate the NMN biosynthesis capability of V. natriegens.

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