Luca Cirfeta

The fourth observing run (O4) of Advanced LIGO, Virgo, and KAGRA presents unparalleled sensitivity, rendering unsupervised pipelines highly vulnerable to the non-stationary domain shift of the detectors' noise manifolds. We present DANTE V3, concluding a longitudinal investigation into unmodeled anomalies during early O4a. By expanding to a multi-scale geometric framework (0.5 s to 4.0 s), we amplify morphological sensitivity, extracting 10,372 unique candidates. To mitigate domain-shift artifacts, we introduce a block-bootstrap Domain Shift Defense (DSD) against a vector-quantized native background index. While 28.3% of candidates survive recalibration, global topological analysis reveals they lack discrete morphological cohesion. The survivors coalesce into a single macro-cluster without compact substructure; we show explicitly that morphological "diffusivity" comparisons used previously are confounded and retire them. Pristine background is even more monolithic (100% in one cluster vs 99.77% for survivors): this topology is a property of the embedding geometry, not of anomaly status. Executing a definitive physical environment monitoring (PEM) cross-correlation defense using an empirically calibrated null, one singleton is vetoed by a control-line coupling, while another survives as an uncatalogued instrumental outlier. Replacing the embedding-similarity cross-detector coincidence test with a physical normalized cross-correlation test, we find no coincident events among 8,749 candidates. We quote 90% frequentist Poisson upper limits on the rate of novel uncatalogued instrumental morphologies -- $R_{90} \le 5.83 \mathrm{yr}^{-1}$ (H1) and $R_{90} \le 5.63 \mathrm{yr}^{-1}$ (L1). This underscores the absolute necessity of native background recalibration and physical auxiliary vetoes in unsupervised gravitational-wave astronomy.