Biochemistry

A multifunctional polyketide synthase in nematodes produces divergent families of signaling molecules that control different developmental arrests

A multifunctional polyketide synthase in nemat...

Biochemistry
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librarian
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Structural Characterization of Calcium-Dependent Calmodulin-Calmidazolium Binding using Capillary Vibrating Sharp-Edge Spray-based Native Mass Spectrometry and In-Droplet Hydrogen Deuterium Exchange Mass Spectrometry

Structural Characterization of Calcium-Depende...

Biochemistry
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librarian
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Reparameterization of the Amber RNA Force Field Non-Bonded Terms

Reparameterization of the Amber RNA Force Fiel...

Biochemistry
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librarian
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Cholesterol links blood feeding to mosquito development and reproduction

Cholesterol links blood feeding to mosquito de...

Biochemistry
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Yoram Gerchman
5 views
Disease-associated mutations in TPM2 alter regulation of actin filament stability and cofilin-dependent dynamics

Disease-associated mutations in TPM2 alter reg...

Biochemistry
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Joanna Moraczewska
4 views
Structure of the human HIRA histone chaperone with a nucleosome suggests a stepwise nucleosome assembly mechanism

Structure of the human HIRA histone chaperone ...

Biochemistry
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librarian
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Mcm10 braces converging replicative helicases to pull apart origin DNA

Mcm10 braces converging replicative helicases ...

Biochemistry
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librarian
14 views
Evolution of allostery without shape shifting: Internal dynamics drives functional diversification of a transcriptional repressor superfamily

Evolution of allostery without shape shifting:...

Biochemistry
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librarian
6 views
Symmetry Analysis and Ancestral Sequence Reconstruction Reveal a Symmetrical Translocation Pathway and Activity Determinants of ZIP Metal Transporter

Symmetry Analysis and Ancestral Sequence Recon...

Biochemistry
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librarian
11 views
Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase

Potent reaction hijacking inhibitors of Plasmo...

Biochemistry
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Miles Siegel
12 views
Structure and inhibition of the sperm TMEM95-FIMP complex in mammalian fertilization

Structure and inhibition of the sperm TMEM95-F...

Biochemistry
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Shaogeng Tang
11 views
Mouse Fc-FcγRIV structure guides Fc engineering for cross-species FcγR recognition

Mouse Fc-FcγRIV structure guides Fc engineerin...

Biochemistry
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librarian
10 views
Hsp10: From Single to Double Rings-Structural Basis of Protein Homeostasis

Hsp10: From Single to Double Rings-Structural ...

Biochemistry
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librarian
16 views
Small-molecule modulators of HIPK4 activity and proteostasis

Small-molecule modulators of HIPK4 activity an...

Biochemistry
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Thomas Chung
15 views
Mass spectrometric analysis of free methionine oxidation levels in E. coli

Mass spectrometric analysis of free methionine...

Biochemistry
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librarian
11 views
Structure and Mechanism of a Two-component Lanthipeptide Toxin

Structure and Mechanism of a Two-component Lan...

Biochemistry
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Ryan Moreira
10 views
A nested shell structure coordinates enzyme communication in pyruvate oxidation

A nested shell structure coordinates enzyme co...

Biochemistry
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librarian
12 views
OptiFoot: a method for recording protein footprints on DNA for microscopy and sequence analysis

OptiFoot: a method for recording protein footp...

Biochemistry
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librarian
15 views
Dual-Lipa: A sequential multi-omic subcellular landscape map of mouse heart

Dual-Lipa: A sequential multi-omic subcellular...

Biochemistry
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librarian
13 views
PARG activity is required for cell death by parthanatos

PARG activity is required for cell death by pa...

Biochemistry
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librarian
15 views
Phytochemical profiling and antioxidant potential of freshwater algal extracts from Lahore, Pakistan, with preliminary evaluation of cytotoxic activity

Phytochemical profiling and antioxidant potent...

Biochemistry
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librarian
12 views
Structural basis for Ca2+-dependent, RyR2-selective stabilization by Ryanozole in CPVT

Structural basis for Ca2+-dependent, RyR2-sele...

Biochemistry
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librarian
13 views
Substrate-derived peptides for selective covalent inhibition of protein tyrosine kinases

Substrate-derived peptides for selective coval...

Biochemistry
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librarian
14 views
Biophysical and enzymatic comparison of Bacillus safensis and Bacillus subtilis malate dehydrogenase (MDH) enzymes

Biophysical and enzymatic comparison of Bacill...

Biochemistry
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librarian
15 views
Iterative structural homology search identifies new substrates of the protein O-fucosyltransferases POFUT3 and POFUT4

Iterative structural homology search identifie...

Biochemistry
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librarian
14 views
dsRADAR: Imaging and Quantifying Cellular dsRNA by Repurposing RNA Binding Proteins

dsRADAR: Imaging and Quantifying Cellular dsRN...

Biochemistry
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Jennifer Heemstra
17 views
Structural and kinetic insights into a metagenomics-derived Cas12a with high specificity

Structural and kinetic insights into a metagen...

Biochemistry
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Tyler Dangerfield
14 views
Conformational Expansion Underlies the Evolutionary Emergence of Redox Sensitivity in Vertebrate Glucokinases

Conformational Expansion Underlies the Evoluti...

Biochemistry
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librarian
17 views
Chronic elevation of 1.25(OH)2D enhances cholesterol excretion through coordinated regulation of hepatic and intestinal elimination pathways

Chronic elevation of 1.25(OH)2D enhances chole...

Biochemistry
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Chiaki Abe
20 views
Specificity Profiling of the RhoGEF Domain of EhFP10 with EhRho GTPases Involved in Cytoskeleton Remodeling

Specificity Profiling of the RhoGEF Domain of ...

Biochemistry
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Samudrala Gourinath
16 views
Crude Fucus vesiculosus fucoidan demonstrates superior SARS-CoV-2 antiviral activity compared to its pure form: binding kinetics and functional studies

Crude Fucus vesiculosus fucoidan demonstrates ...

Biochemistry
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librarian
14 views
PCanPIE: A group I intron platform for efficient circRNA synthesis at ambient temperatures

PCanPIE: A group I intron platform for efficie...

Biochemistry
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librarian
20 views
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