Molecular Biology

A novel Notch and WNT signaling mechanism contribute to pediatric DCM: a pathway to new therapeutics.
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Carmen Sucharov
2 views
Quantitative Assessment of Protein-DNA Interactions via SYBR Green Fluorescence
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Yucheng Wang
2 views
The apoptosis gene BCL-X splice isoforms have opposing effects in diabetic kidney disease: potential treatment target and prognostic value
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Sebastian Oltean
2 views
Negative epistasis limits current codon optimization approaches
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Zrinka Raguz Nakic
11 views
Uncovering Host-Parasite Dynamics: Gene Expression Shifts in Hematodinium-infected Chionoecetes bairdi in Response to Temperature ChangeChanges in gene expression under differing temperature regimes of infected Chionoecetes bairdi and the parasitic dinoflagellate Hematodinium sp.
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librarian
12 views
IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in Jak2V617F clonal hematopoiesis-driven atherosclerosis.
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Mojdeh Tavallaie
13 views
Dynamic DnaA-DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication
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Tsutomu Katayama
16 views
Designing a broad-spectrum four-helix bundle targeting different strains of SARS-CoV-2 Spike Receptor Binding Domains with ACE2-like binding interface
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librarian
14 views
The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome
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librarian
14 views
SOX2 and SOX9 as Transcriptional Regulators of human Galectin-3 in SW1353 Cells: Potential Implications for Osteoarthritis
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librarian
29 views
Dcaf17 knockdown integrates mitochondrial-lysosomal dysfunction with ferroptosis, NLRP3 inflammasome signaling and necroptosis
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librarian
26 views
Mechanobiological proximal tubular defects in ARC syndrome: A VPS33B CRISPR knockout study
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librarian
21 views
Structural insights into context-specific inhibition of bacterial translation by macrolides
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librarian
22 views
The endoribonuclease Rae1 from Bacillus subtilis cleaves mRNA upstream of stalled ribosomes
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librarian
21 views
DiffDock-Glide: a hybrid physics-based and data-driven approach to molecular docking
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Steven Jerome
21 views
Cytokine expression profile in the human brain of older adults
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Katia Lopes
27 views
Translation-specific disruption of Col1a1 expression in multiple models of Spinal Muscular Atrophy can be rescued by Risdiplam.
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Gabriella Viero
29 views
Single cell multiomic analysis of the impact of Delta-9-tetrahydrocannabinol on HIV infected CD4 T cells
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librarian
25 views
Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids
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Seongmin Jang
31 views
A minimal hybridization capture system for the parallel enrichment and cost-effective detection of ancient human pathogens
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librarian
38 views
Genetic response to light and carbon source variations in Trichoderma harzianum: The key regulatory roles of env1, cre1, and blr2
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librarian
37 views
SR9009 Regulates Macrophage Polarization via the NR1D1/NF-κB Axis to Ameliorate Obesity Associated Ulcerative Colitis
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Zhi Xue Zheng
46 views
Development of a CRISPR/Cas9-induced gene editing system for Pseudoalteromona fuliginea and its applications in functional genomics
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librarian
43 views