Systems Biology

Co-expression network analysis reveals repression of Igf2bp2 by REV-ERBβ in skeletal muscle

Co-expression network analysis reveals repress...

Systems Biology
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librarian
76 views
Coarse-graining metabolic networks via feature learning reveals cross-species growth laws

Coarse-graining metabolic networks via feature...

Systems Biology
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librarian
69 views
Simultaneous single-cell profiling of the transcriptome and proteome

Simultaneous single-cell profiling of the tran...

Systems Biology
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Alex de Marco
72 views
Protein Stability, Turnover Kinetics, and Abundance Constrain the Scaling of Protein Interaction Networks

Protein Stability, Turnover Kinetics, and Abun...

Systems Biology
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librarian
79 views
Global quantification of mammalian gene expression noise

Global quantification of mammalian gene expres...

Systems Biology
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librarian
90 views
MechAInistic: An LLM-guided Multi-Agent System for Reasoning over Genome-Scale Constraint-Based Metabolic Models

MechAInistic: An LLM-guided Multi-Agent System...

Systems Biology
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Josh Loecker
110 views
Uncertainty-aware graph representation learning with positive-unlabeled classification for biomarker discovery in peripheral artery disease

Uncertainty-aware graph representation learnin...

Systems Biology
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Venkat Ayyalasomayajula
78 views
Efficient Bayesian inference for ordinary differential equation models from experimental data with uncertain measurement times

Efficient Bayesian inference for ordinary diff...

Systems Biology
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librarian
76 views
A multiomic lifespan signature in genetically diverse, diet-restricted mice

A multiomic lifespan signature in genetically ...

Systems Biology
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librarian
92 views
Spatially resolved transcriptomic and proteomic profiling reveals cell interaction programs that predict Barrett's esophagus progression

Spatially resolved transcriptomic and proteomi...

Systems Biology
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librarian
87 views
Susagi: A Microbiome World Model

Susagi: A Microbiome World Model

Systems Biology
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librarian
102 views
Homeostatic feedback model of energy metabolism with adaptive enzyme levels exhibits problem solving behavior

Homeostatic feedback model of energy metabolis...

Systems Biology
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Michael Levin
88 views
Talk2QSP: Deriving Executable Scenarios from Unstructured Literature via Human-in-the-Loop Agents

Talk2QSP: Deriving Executable Scenarios from U...

Systems Biology
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librarian
75 views
Learning activator-inhibitor dynamics at the cell cortex with neural likelihood ratio estimation

Learning activator-inhibitor dynamics at the c...

Systems Biology
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Ondrej Maxian
91 views
Systemic stress states are reversed by NPBWR1 inhibition

Systemic stress states are reversed by NPBWR1 ...

Systems Biology
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librarian
85 views
Unraveling the metabolic interactions of a Dehalobacter-containinganaerobic mixed culture for bioremediation

Unraveling the metabolic interactions of a Deh...

Systems Biology
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librarian
82 views
Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosures

Scalable longitudinal imaging and transcriptom...

Systems Biology
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Mostafa Ronaghi
107 views
Mathematical Modeling of the Canonical Aryl Hydrocarbon Receptor Pathway

Mathematical Modeling of the Canonical Aryl Hy...

Systems Biology
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librarian
79 views
Ensemble kinetic modelling links residual enzyme activity to clinical symptoms in mitochondrial β-oxidation defects

Ensemble kinetic modelling links residual enzy...

Systems Biology
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librarian
92 views
A unified framework links infant vulnerability with aging-related mortality dynamics

A unified framework links infant vulnerability...

Systems Biology
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librarian
84 views
COCOA.jl: A Julia package for high-performance analysis of concordance and kinetic modules in biochemical networks

COCOA.jl: A Julia package for high-performance...

Systems Biology
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librarian
83 views
Robotic perturbation proteomics and AI agents enable scalable drug mechanism discovery

Robotic perturbation proteomics and AI agents ...

Systems Biology
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Yuming Jiang
113 views
Multi-omic analysis identifies mitochondrial dysfunction as a conserved driver of acute severity and long-term complications in RSV infection

Multi-omic analysis identifies mitochondrial d...

Systems Biology
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librarian
86 views
Bion-M 2 Biosatellite: Multisystem Mouse Responses to 30 Days in High-Latitude Orbit as a Deep-Space Analog

Bion-M 2 Biosatellite: Multisystem Mouse Respo...

Systems Biology
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librarian
89 views
Box-Counting Fractal Dimensions of Cranial Suture: Effects of Measurement Conditions and Model-Based Reproduction of Fractal-Like Patterns

Box-Counting Fractal Dimensions of Cranial Sut...

Systems Biology
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Takashi Miura
84 views
Lineage-specific lncRNAs critically determine cross-species differences in tumors

Lineage-specific lncRNAs critically determine ...

Systems Biology
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librarian
90 views
REDUCED-PRECISION STOCHASTIC SIMULATION FOR MATHEMATICAL BIOLOGY

REDUCED-PRECISION STOCHASTIC SIMULATION FOR MA...

Systems Biology
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librarian
86 views
Network topology dictates sequential drug efficacy through bistability-mediated state switching

Network topology dictates sequential drug effi...

Systems Biology
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librarian
101 views
The Limits of Cross-Species WGCNA: Library Imbalance and Signal Dilution Constrain Effector Gene Recovery in Dual-Organism RNA-seq

The Limits of Cross-Species WGCNA: Library Imb...

Systems Biology
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librarian
94 views
Systems modeling identifies phenotype-determining signaling pathways controlled by phosphatase PTPRJ in diverse receptor tyrosine kinase activation settings

Systems modeling identifies phenotype-determin...

Systems Biology
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librarian
85 views
A Scalable Sign-Aware Multi-Omics Knowledge Graph Foundation Model for Mechanistic Drug Action and Clinical Response Predictions

A Scalable Sign-Aware Multi-Omics Knowledge Gr...

Systems Biology
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Lei Xie
105 views
A Comprehensive Mathematical Model of Avidity in Cytokine Signaling

A Comprehensive Mathematical Model of Avidity ...

Systems Biology
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librarian
83 views
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