Bioinformatics

Phenotypic inference from sparse tumor genomes informs an explainable deep-learning model for cancer prognosis

Phenotypic inference from sparse tumor genomes...

Bioinformatics
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Aritro Nath
5 views
BOSE: A Bayesian Order Statistics-Based Estimator for Recovering the Sample Mean and Standard Deviation

BOSE: A Bayesian Order Statistics-Based Estima...

Bioinformatics
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librarian
4 views
Impacts of batch effects on the performance of machine learning classifiers across multiple studies

Impacts of batch effects on the performance of...

Bioinformatics
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librarian
7 views
A Robust Machine Learning Framework for Keloid Biomarker Discovery Beyond Differential Expression

A Robust Machine Learning Framework for Keloid...

Bioinformatics
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Ali Daher
5 views
Context-dependent correlations mislead transcriptomic network inference in bulk and single-cell data

Context-dependent correlations mislead transcr...

Bioinformatics
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librarian
13 views
Single-cell transcriptomics reveals chondrocyte state transitions and ECM remodeling in osteoarthritic knee cartilage

Single-cell transcriptomics reveals chondrocyt...

Bioinformatics
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librarian
13 views
Learning Fragmentation Physics or Exploiting Sequence Priors? Benchmarking Bias in Deep Learning Models for De Novo Peptide Sequencing

Learning Fragmentation Physics or Exploiting S...

Bioinformatics
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librarian
10 views
Practical Use of Advanced AI Frameworks on Real-Life Scientific Problems: Three Case Studies

Practical Use of Advanced AI Frameworks on Rea...

Bioinformatics
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Halime Gulluoglu
11 views
A hyperbolic topological atlas reveals polyamine steering of a shared developmental manifold in Arabidopsis

A hyperbolic topological atlas reveals polyami...

Bioinformatics
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librarian
10 views
MassSpectrum Analyzer: An interactive platform for proteomic searching parameter refinement and peptide modification focused re-scoring

MassSpectrum Analyzer: An interactive platform...

Bioinformatics
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librarian
17 views
Desktop-Scale Hit-Point Discovery for Intrinsically Disordered α-Synuclein Using State-Space Compression and a Discrete Phase-Interference Search Operator

Desktop-Scale Hit-Point Discovery for Intrinsi...

Bioinformatics
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Dae Hoon Kim
19 views
Short-Read Sequencing Benchmarking with Donor-Specific Assemblies

Short-Read Sequencing Benchmarking with Donor-...

Bioinformatics
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Chia-Lin Wei
20 views
PARROT: Phase-Altering Regulatory Rewiring Over Time

PARROT: Phase-Altering Regulatory Rewiring Ove...

Bioinformatics
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librarian
19 views
Lineage-aware stochastic modeling reveals gene-expression dynamics in development and disease

Lineage-aware stochastic modeling reveals gene...

Bioinformatics
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librarian
19 views
eRNAformer enables genome-wide de novo mapping of enhancer-derived RNA loci

eRNAformer enables genome-wide de novo mapping...

Bioinformatics
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Hua Yu
26 views
Glitch genes: embedding geometry predicts functional fragility in single-cell foundation models

Glitch genes: embedding geometry predicts func...

Bioinformatics
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Justin Whalley
17 views
ProLoc: Text-guided Localization of Protein Functional Regions

ProLoc: Text-guided Localization of Protein Fu...

Bioinformatics
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Peishuo Liu
19 views
Agentic AI for Structural Elucidation and Discovery of Drug Metabolites from Mass Spectrometry Data

Agentic AI for Structural Elucidation and Disc...

Bioinformatics
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librarian
26 views
A Snakemake-based bacterial whole genome comparison pipeline for multi-group clinical isolates

A Snakemake-based bacterial whole genome compa...

Bioinformatics
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librarian
26 views
Development of Deep-Learning Models that Predict Quantitative Protein-Ligand Interac-tions in Glycobiology as a part of a Capstone Course

Development of Deep-Learning Models that Predi...

Bioinformatics
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librarian
31 views
Beyond statistical significance: ranking transcription factor binding motifs by effect size

Beyond statistical significance: ranking trans...

Bioinformatics
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librarian
29 views
EnrichViz: An Interactive R Shiny Application for Visualization of Pathway Enrichment Results from Omics Data

EnrichViz: An Interactive R Shiny Application ...

Bioinformatics
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Rolando Garcia-Milian
40 views
Multi-Scale Machine Learning for Antibody-Antigen Binding Affinity Prediction Using Deep Mutational Scanning and Structural Features

Multi-Scale Machine Learning for Antibody-Anti...

Bioinformatics
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Santhosh Sivasubramani
26 views
Early Tracheal and Salivary miRNAs in Extremely Preterm Infants Predict BPD-related Pulmonary Hypertension

Early Tracheal and Salivary miRNAs in Extremel...

Bioinformatics
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librarian
27 views
Complex-valued representations of time-series gene expression profiles for network analysis

Complex-valued representations of time-series ...

Bioinformatics
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Jianqiang Sun
26 views
Expanding the GUSome: Structure-guided identification and characterization of gut microbial β-glucuronidases

Expanding the GUSome: Structure-guided identif...

Bioinformatics
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Subhash Bihani
33 views
Geometric Deep Learning Reveals Ligandable and Cryptic RNA Binding Small Molecule Pockets (SMARTPocket)

Geometric Deep Learning Reveals Ligandable and...

Bioinformatics
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librarian
56 views
SteerAF: Distogram-based Steering of AlphaFold2 toward Alternative Conformations

SteerAF: Distogram-based Steering of AlphaFold...

Bioinformatics
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librarian
53 views
OmniPath Metabo: chemical structures, interactions and mechanisms to study the metabolome

OmniPath Metabo: chemical structures, interact...

Bioinformatics
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librarian
45 views
Structure Bioinformatics of Eight Human ATP Synthase Fo Subunits and Their AlphaFold3-Predicted Water-Soluble QTY Analogs

Structure Bioinformatics of Eight Human ATP Sy...

Bioinformatics
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librarian
47 views
Structure-Based Immunoinformatics Design of a CTB-Adjuvanted Multi-Epitope Mucosal Vaccine Against Helicobacter pylori

Structure-Based Immunoinformatics Design of a ...

Bioinformatics
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Razieh Veisi
45 views
Predicting optimal growth temperatures of bacteria using learned structural information from a single protein

Predicting optimal growth temperatures of bact...

Bioinformatics
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Michael Hoffert
43 views
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