Bioinformatics

Modeling gene regulatory perturbations via deep learning from high-throughput reporter assays

Modeling gene regulatory perturbations via dee...

Bioinformatics
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William Majoros
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BCAR: A fast and general barcode-sequence mapper for correcting sequencing errors

BCAR: A fast and general barcode-sequence mapp...

Bioinformatics
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librarian
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Structured Pooling Improves Detection of Rare Regulatory Mutations in Population-Scale Reporter Assays

Structured Pooling Improves Detection of Rare ...

Bioinformatics
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librarian
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WayFindR: Investigating Feedback in Biological Pathways

WayFindR: Investigating Feedback in Biological...

Bioinformatics
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librarian
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Clinical evidence yield as a framework for evaluating computational predictors and multiplexed assays of variant effect

Clinical evidence yield as a framework for eva...

Bioinformatics
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librarian
2 views
ALPINE: A Scalable Pipeline for Comprehensive Classification of Gene-Editing Outcomes from Long-Read Amplicon Sequencing

ALPINE: A Scalable Pipeline for Comprehensive ...

Bioinformatics
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Yu Chen
3 views
IDBSpred: An intrinsically disordered binding site predictor using machine learning and protein language model

IDBSpred: An intrinsically disordered binding ...

Bioinformatics
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librarian
1 view
FoldaVirus, a knowledge-based icosahedral capsid builder using AlphaFold

FoldaVirus, a knowledge-based icosahedral caps...

Bioinformatics
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librarian
0 views
Panmap: Scalable phylogeny-guided alignment, genotyping, and placement on pangenomes

Panmap: Scalable phylogeny-guided alignment, g...

Bioinformatics
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librarian
1 view
deluxpore: a Nextflow pipeline for demultiplexing Illumina dual-indexed Nanopore libraries

deluxpore: a Nextflow pipeline for demultiplex...

Bioinformatics
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Jaime Huerta-Cepas
2 views
Transposable elements as new players to decipher sex differences in Parkinson Disease

Transposable elements as new players to deciph...

Bioinformatics
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Mie Kobayashi-Ishihara
4 views
Epigenomic methylome landscape of promoters in vertebrate genomes

Epigenomic methylome landscape of promoters in...

Bioinformatics
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librarian
3 views
SpacerScope: Binary-vectorized, genome-wide off-target profiling for RNA-guided nucleases without prior candidate-site bias

SpacerScope: Binary-vectorized, genome-wide of...

Bioinformatics
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Yanji Qu
2 views
Lemonite: identification of regulatory metabolites through data-driven, interpretable integration of transcriptomics and metabolomics data

Lemonite: identification of regulatory metabol...

Bioinformatics
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librarian
2 views
MAAMOUL: Metabolic network-based discovery of microbiome-metabolome shifts in disease

MAAMOUL: Metabolic network-based discovery of ...

Bioinformatics
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librarian
1 view
DualLoc: Full-parameter fine-tuning of cascaded dual transformers for protein subcellular localization prediction

DualLoc: Full-parameter fine-tuning of cascade...

Bioinformatics
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librarian
1 view
PHENOCAUZ: Linking Human Symptoms, Drug Side Effects and Efficacy to Their Molecular Causes Using Mendelian Disease Biology

PHENOCAUZ: Linking Human Symptoms, Drug Side E...

Bioinformatics
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Jeffrey Skolnick
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Cellector: A tool to detect foreign genotype cells in scRNAseq data with applications in leukemia and microchimerism.

Cellector: A tool to detect foreign genotype c...

Bioinformatics
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librarian
1 view
CCIDeconv: Hierarchical model for deconvolution of subcellular cell-cell interactions in single-cell data

CCIDeconv: Hierarchical model for deconvolutio...

Bioinformatics
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librarian
0 views
Symmetric Self-play Online Preference Optimization for Protein Inverse Folding

Symmetric Self-play Online Preference Optimiza...

Bioinformatics
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librarian
0 views
Computational Development of a GluN1 Synthetic Peptide Mimetic for Neutralization of Autoantibodies in Anti-NMDAR Autoimmune Encephalitis

Computational Development of a GluN1 Synthetic...

Bioinformatics
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Ravi Shah
1 view
MOAflow: how re-design a pipeline with Nextflow streamlines data analysis

MOAflow: how re-design a pipeline with Nextflo...

Bioinformatics
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librarian
0 views
BrainYears: A functional EEG-based brain age clock enables intervention-ready measurements of brain aging

BrainYears: A functional EEG-based brain age c...

Bioinformatics
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Eric Verdin
2 views
Track Hub Quickload Translator: Convert Track Hub or Quickload data for viewing in the UCSC Genome Browser or the Integrated Genome Browser

Track Hub Quickload Translator: Convert Track ...

Bioinformatics
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librarian
2 views
Evolutionary exploration of drug-like chemical space utilizing generative AI and virtual screening

Evolutionary exploration of drug-like chemical...

Bioinformatics
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librarian
2 views
methbiome: reference-based DNA methylation profiling of long-read metagenomic data

methbiome: reference-based DNA methylation pro...

Bioinformatics
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librarian
2 views
ClumPyCells resolves spatial aggregation in complex tissues overcoming size biases

ClumPyCells resolves spatial aggregation in co...

Bioinformatics
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Eugenia Flores-Figueroa
2 views
Evolutionary history of ligand binding by the LRR domain of innate immunity receptors: the story of the TLR2 cavity

Evolutionary history of ligand binding by the ...

Bioinformatics
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Adam Godzik
2 views
Evolutionary history of ligand binding by the LRR domain of innate immunity receptors: the story of the TLR2 cavity

Evolutionary history of ligand binding by the ...

Bioinformatics
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Adam Godzik
8 views
Deciphering sepsis molecular subtypes using large-scale data to identify subtype-specific drug repurposing

Deciphering sepsis molecular subtypes using la...

Bioinformatics
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librarian
1 view
A run-length-compressed skiplist data structure for dynamic GBWTs supports time and space efficient pangenome operations over syncmers

A run-length-compressed skiplist data structur...

Bioinformatics
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librarian
2 views
Variable Resolution Maps (VRM) in CCTBX and Phenix: Accounting For Local Resolution In cryoEM

Variable Resolution Maps (VRM) in CCTBX and Ph...

Bioinformatics
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librarian
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