Synthetic Biology

Metabolic engineering of Escherichia coli to modulate hydrogen sulfide levels in the mammalian gut
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librarian
103 views
Automated design of stiffness-tunable DNA origami hollowframes for self-assembling metamaterials
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Rebecca Taylor
134 views
Tailoring Precise Genomic Integration Toward Isolate-to-Industry Strain Development for Scalable High-Titer Production of Polyhydroxyalkanoate
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librarian
111 views
Division of Synthetic Cells Using a Genomically Encoded One-Protein Divisome
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librarian
108 views
Continuous target-specific mutagenesis and rapid gene evolution by diversity-generating retroelements in Escherichia coli
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Yang Liu
116 views
Seven mutations unlock strict synthetic methylotrophy in engineered Pseudomonas putida
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Òscar Puiggené
128 views
Programming the Internal Architecture of Synthetic Compartments by Coassembling Filamentous and Liquid DNA Phases
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librarian
112 views
Polymerase Evolution Enables Access to Glycosylated Xeno-Nucleic Acids with Expanded Chemical Functionality
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librarian
135 views
Continuous site-directed mutagenesis and selection in Escherichia coli
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Fabian Rehm
115 views
Hexadecimal data encryption in paranemic crossover (PX) DNA
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librarian
138 views
Synthesis of Ultra-Large Fibrous Proteins from Bacteria via a Looped-Translation System
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librarian
104 views
Pharmacologically regulated bioorthogonal stabilization domain for regulation of CAR T cells
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librarian
134 views
Overcoming protocatechuate and catechol accumulation in muconic acid production via adaptive laboratory evolution and metabolic engineering in Pseudomonas putida
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Alissa Bleem
131 views
Engineered Pseudomonas putida reconfigures metabolic fluxes to support energy demands during muconate bioproduction from lignin-related aromatics
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Allison Werner
134 views
Storing >1 byte of information in 16S ribosomal RNA using orthogonal trans-splicing ribozymes
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librarian
158 views
Pathway selection for arabinose utilization in Pseudomonas putida reveals a rate-yield tradeoff in muconic acid production from lignocellulosic sugars
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Davinia Salvachúa
129 views
Biocontainment attenuation of mobile DNA host range in a wastewater microbiome
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librarian
146 views
Minimal Data, Maximal Insight (MDMI): A Structure-guided Pipeline for Discovering Functional Alternatives in Peptide-Protein Interfaces
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Keith Pardee
123 views
Programmable and Dynamic DNA Localisation at Synthetic Cell Membranes
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librarian
135 views
A microbial growth-coupled platform for in vivo interrogation of Rubisco oxygenase activity
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Enrico Orsi
136 views
BxbI-mediated insertion of a 77kb human RET sensitive haplotype into the mouse genome to generate a humanized model of Hirschsprung disease
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librarian
129 views
Extracellular injection system combined with peptides for intracellular Staphylococcus aureus treatment
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Ningning Song
132 views
MozClo: An Expanded MoClo Toolset for Large Multigene Assembly and Plant Transformations
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Cory Tobin
142 views
Transcription-induced coacervation accelerates and sensitizes cell-free biosensing
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Samanvaya Srivastava
133 views
AAV delivered lysosome-targeting chimeras mediate sustained antibody depletion in vivo
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librarian
131 views
Fabrication and Use of a 32-Well LED-Embedded Microplate for Optogenetic Dynamic Control
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librarian
123 views
Deoxyribonucleotide incorporation reshapes mRNA design beyond canonical ribonucleotide boundaries
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Joseph Rosenecker
134 views
An Unusual Follower Peptide is Required for Biosynthesis of the Antibiotic Lasso Peptide Triculamin
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librarian
131 views
Domain Insertion Improves the Precision of a CRISPR Adenine Base Editor
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librarian
139 views
Engineered probiotic Escherichia coli-mediated intestinal nicotine clearance alleviates nonalcoholic steatohepatitis in mice
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Xin Song
121 views
Directed evolution of compact synthetic promoters via AlphaGenome and genetic algorithms
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Linxiao Nie
143 views
Linker-Length Landscape Mapping Enables Coupling of Diverse Synthetic Chemically Induced Dimerization Systems to Molecular Readouts
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librarian
128 views