Cancer Biology

Elongin B orchestrates chromatin and transcriptional programs in H3K27M-mutant diffuse midline glioma

Elongin B orchestrates chromatin and transcrip...

Cancer Biology
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librarian
48 views
Tumoral Switch in NUMB splicing changes essential transcription pathways and induces malignant properties in tumour cells

Tumoral Switch in NUMB splicing changes essent...

Cancer Biology
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librarian
53 views
β-Hydroxybutyrate elicits divergent metabolic responses between MCF-7 and T47D ER+ breast cancer cells under glucose restriction

β-Hydroxybutyrate elicits divergent metabolic ...

Cancer Biology
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Michael Weichhaus
45 views
MYC overexpression drives poor prognosis and differential sensitivity to treatments according to TP53 status in chronic lymphocytic leukemia

MYC overexpression drives poor prognosis and d...

Cancer Biology
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María Hernández-Sánchez
37 views
Cellular stemness identifies high-risk ductal carcinoma in situ and offers a therapeutic interception opportunity

Cellular stemness identifies high-risk ductal ...

Cancer Biology
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librarian
54 views
Neutral Sphingomyelinase-2 Restrains TAZ to Suppress Breast Tumor Growth

Neutral Sphingomyelinase-2 Restrains TAZ to Su...

Cancer Biology
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librarian
48 views
LVV SMRTcap reveals extensive proviral variation in lentiviral vector-transduced CAR T cells

LVV SMRTcap reveals extensive proviral variati...

Cancer Biology
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librarian
46 views
Genomic, Clinical, and Spatial Predictors of Durable Response to BRAF/MEK Inhibition in BRAF-Mutant Melanoma

Genomic, Clinical, and Spatial Predictors of D...

Cancer Biology
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librarian
35 views
Purinergic signaling promotes gliomagenesis through nuclear calcium transients

Purinergic signaling promotes gliomagenesis th...

Cancer Biology
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librarian
33 views
Glutamatergic neuron-tumor synapses shape human glioblastoma cell states through radial glia plasticity

Glutamatergic neuron-tumor synapses shape huma...

Cancer Biology
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librarian
44 views
Cell line-dependent effects of spheroid formation method on drug response in melanoma models

Cell line-dependent effects of spheroid format...

Cancer Biology
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Akvilė Žilytė
44 views
Integrated spatial and single-cell transcriptomic analysis of aggressive glioblastoma growth dynamics.

Integrated spatial and single-cell transcripto...

Cancer Biology
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librarian
47 views
Compact serum miRNA qPCR model for pancreatic cancer discrimination with independent and clinical validation

Compact serum miRNA qPCR model for pancreatic ...

Cancer Biology
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Yoshitake Sano
48 views
FASN Inhibition Resensitizes Chordoma to Radiotherapy by Targeting Adaptive Unsaturated Fatty Acid Metabolism

FASN Inhibition Resensitizes Chordoma to Radio...

Cancer Biology
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librarian
42 views
Integrated Collagen Architecture and Composition Improve Risk Stratification in Triple-Negative Breast Cancer

Integrated Collagen Architecture and Compositi...

Cancer Biology
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librarian
39 views
Functional T cells trapped behind a stromal wall: a Brake-with-Wall phenotype redefines pancreatic adenocarcinoma immunotherapy resistance

Functional T cells trapped behind a stromal wa...

Cancer Biology
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Jeong-Soon Yong
170 views
The miR-221-5p/RAD18/RAD51 axis regulates DNA damage tolerance and homologous recombination to drive platinum resistance in ovarian cancer.

The miR-221-5p/RAD18/RAD51 axis regulates DNA ...

Cancer Biology
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Komaraiah Palle
40 views
The CNS-penetrant MAP4K inhibitor famlasertib restrains medulloblastoma dissemination without developmental toxicity

The CNS-penetrant MAP4K inhibitor famlasertib ...

Cancer Biology
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librarian
37 views
Ablation of glypican-3 enhances radiosensitivity in liver cancer by prolonging G2/M arrest and activating the ATM/CHK2 pathway

Ablation of glypican-3 enhances radiosensitivi...

Cancer Biology
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Joon-Yong Chung
79 views
Profilin-1 Promotes Chromophobe Renal Cell Carcinoma Malignancy

Profilin-1 Promotes Chromophobe Renal Cell Car...

Cancer Biology
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librarian
34 views
TumorArchetypeR: A modular framework to derive signature-based tumor subtypes

TumorArchetypeR: A modular framework to derive...

Cancer Biology
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librarian
40 views
Collective cancer cell calcium activity drives brain metastasis

Collective cancer cell calcium activity drives...

Cancer Biology
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librarian
47 views
Neuroendocrine-like/EMT dedifferentiation mediates resistance to EGFR inhibitors via the NRG1/HER3 axis

Neuroendocrine-like/EMT dedifferentiation medi...

Cancer Biology
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Mattia Lauriola
48 views
SOCS1 expression in prostate epithelial cells is essential for tissue homeostasis and tumor suppression

SOCS1 expression in prostate epithelial cells ...

Cancer Biology
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librarian
48 views
Inhibition of the Adenosine pathway activates the immune response against Mesothelioma.

Inhibition of the Adenosine pathway activates ...

Cancer Biology
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Brittany Magalis
49 views
Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14

Astrocyte immunosuppressive activity in gliobl...

Cancer Biology
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librarian
39 views
A computational model reveals that spatial localization of cancer stem cells increases radioresistance in tumorspheres

A computational model reveals that spatial loc...

Cancer Biology
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librarian
52 views
Efficacy evaluation of glasedgib Sonic Hedgehog pathway inhibition with or without inotuzumab in B-ALL cells using a new co-culturing system model and a validated chemosensitivity assay

Efficacy evaluation of glasedgib Sonic Hedgeho...

Cancer Biology
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Cecilia Yeung
49 views
Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas

Targeting an RNA Editor to Impede H3K27M+ Pedi...

Cancer Biology
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librarian
58 views
Machine Learning Analysis to Define Cell Lineage in Leiomyosarcoma

Machine Learning Analysis to Define Cell Linea...

Cancer Biology
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librarian
46 views
Tumor-associated tissue-resident macrophages drive pancreatic cancer progression through IGF1-IGF1R signaling

Tumor-associated tissue-resident macrophages d...

Cancer Biology
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Naoki Tanimizu
42 views
Antibody Blockade of Ly49/MHC-I interactions enhances Innate and Adaptive Immunity Against Cancer Metastasis

Antibody Blockade of Ly49/MHC-I interactions e...

Cancer Biology
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librarian
44 views
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