Cancer Biology

Stromal asparagine supports tumor adaptation to oxidative phosphorylation inhibition through SLC38A4-mediated metabolic coupling

Stromal asparagine supports tumor adaptation t...

Cancer Biology
Avatar
Rui Ju
3 views
Castration-resistant prostate cancer cells are addicted to the high activity of cyclin-dependent kinase 2

Castration-resistant prostate cancer cells are...

Cancer Biology
Avatar
librarian
1 view
TRIM9 switches the morphological phenotype of melanoma cells

TRIM9 switches the morphological phenotype of ...

Cancer Biology
Avatar
Stephanie Gupton
4 views
PI3K-AKT activation determines oncogenic RAS-induced hypertranscription and replication stress

PI3K-AKT activation determines oncogenic RAS-i...

Cancer Biology
Avatar
Eva Petermann
3 views
Co-targeting an AMPK--MAPK axis reprograms CAFs and suppresses PDAC

Co-targeting an AMPK--MAPK axis reprograms CAF...

Cancer Biology
Avatar
Ryodai Yamamura
2 views
Dual targeting of PDPK1 and BRAF V600E is synthetically lethal

Dual targeting of PDPK1 and BRAF V600E is synt...

Cancer Biology
Avatar
Tejinder Pal Khaket
1 view
Cancer Cell Line Encyclopedia Data Suggest that Ligands for ERBB Family Receptors May Drive BRAF-WT Melanomas

Cancer Cell Line Encyclopedia Data Suggest tha...

Cancer Biology
Avatar
librarian
1 view
The Copy-Number Events in Skull Base Chordoma Stratify Tumours into Four Biologically Coherent Groups

The Copy-Number Events in Skull Base Chordoma ...

Cancer Biology
Avatar
Szymon Baluszek
4 views
The bone marrow microenvironment of RAS pathway mutant B-ALL is enriched for immunosuppressive regulatory T cells

The bone marrow microenvironment of RAS pathwa...

Cancer Biology
Avatar
librarian
1 view
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms

NicheSphere reveals Spp1⁺ macrophages as centr...

Cancer Biology
Avatar
librarian
1 view
Principles of subclonal gene dosage across human cancer

Principles of subclonal gene dosage across hum...

Cancer Biology
Avatar
librarian
4 views
Plastin-3 membrane recruitment drives cell-in-cell invasion during entosis

Plastin-3 membrane recruitment drives cell-in-...

Cancer Biology
Avatar
librarian
3 views
Endothelial ACKR1 expression regulates neutrophil infiltration and breast cancer metastatic engraftment in the lung metastatic niche

Endothelial ACKR1 expression regulates neutrop...

Cancer Biology
Avatar
librarian
3 views
Systemic Cysteine Elevation Sustains T-Cell Activation to Potentiate PD-1 Blockade

Systemic Cysteine Elevation Sustains T-Cell Ac...

Cancer Biology
Avatar
Xin Li
2 views
Single-cell RNA editing defines clinically relevant cellular states in chronic myelomonocytic leukemia

Single-cell RNA editing defines clinically rel...

Cancer Biology
Avatar
librarian
4 views
Arginine synthesis pathway and ASS1 play a critical role in mRNA translation reprogramming and ICI resistance in cutaneous melanoma

Arginine synthesis pathway and ASS1 play a cri...

Cancer Biology
Avatar
librarian
2 views
Early microglial activation in the TME enables FLASH-RT to eradicate medulloblastoma while promoting neuron-astrocyte crosstalk to minimize toxicity in the hippocampus

Early microglial activation in the TME enables...

Cancer Biology
Avatar
librarian
2 views
The pyruvate branch point controls lymphoid cancer cell dissemination

The pyruvate branch point controls lymphoid ca...

Cancer Biology
Avatar
Stefan Schieke
3 views
A robust negative association between estimated tumour circadian clock function and survival in early stage breast cancer

A robust negative association between estimate...

Cancer Biology
Avatar
librarian
2 views
eIF4G2-dependent translation restrains pancreatic cancer progression

eIF4G2-dependent translation restrains pancrea...

Cancer Biology
Avatar
Iok In Christine Chio
6 views
ULK1 drives NDP52-mediated selective autophagic degradation of MHC-I to promote immune evasion in HPV-positive head and neck cancer

ULK1 drives NDP52-mediated selective autophagi...

Cancer Biology
Avatar
librarian
2 views
Evidence that the protein phosphatase activity of PTEN contributes to embryonic development and tumour suppression in mice

Evidence that the protein phosphatase activity...

Cancer Biology
Avatar
librarian
2 views
A network-based deep learning model integrating subclonal architecture for therapy response prediction in cancer

A network-based deep learning model integratin...

Cancer Biology
Avatar
librarian
2 views
ATM functions as a rheostat of metabolic stress in small-cell lung cancer

ATM functions as a rheostat of metabolic stres...

Cancer Biology
Avatar
Triparna Sen
2 views
Spatial Agent-Based Modeling and Interpretable Machine Learning Predict Combination Therapy Response in HER2-Heterogeneous Breast Cancer

Spatial Agent-Based Modeling and Interpretable...

Cancer Biology
Avatar
librarian
1 view
Long-Read Transcriptome Sequencing and Functional Validation Reveals Novel and Oncogenic Gene Fusions in Fusion Panel-Negative Gliomas

Long-Read Transcriptome Sequencing and Functio...

Cancer Biology
Avatar
librarian
4 views
POLQ-driven repair scars shape the immunogenic landscape of homologous recombination-deficient pancreatic cancer

POLQ-driven repair scars shape the immunogenic...

Cancer Biology
Avatar
Wungki Park
13 views
RasG12V Oncogene-Induced Epithelial Senescence and Its Relay Promotes Host Metabolic Syndrome in Drosophila

RasG12V Oncogene-Induced Epithelial Senescence...

Cancer Biology
Avatar
librarian
4 views
Italia: A PARP-Directed Auger Electron-Emitting Agent for Targeted Radionuclide Therapy of Cancer

Italia: A PARP-Directed Auger Electron-Emittin...

Cancer Biology
Avatar
librarian
4 views
DNA methylation variability defines a fundamental dimension of tumor epigenomes linked to genomic instability, tumor aggressiveness, and clinical outcomes

DNA methylation variability defines a fundamen...

Cancer Biology
Avatar
librarian
3 views
Integrated single-cell and spatial transcriptomic analysis of T cell exhaustion and immunometabolic remodeling in HPV-positive oropharyngeal squamous cell carcinoma

Integrated single-cell and spatial transcripto...

Cancer Biology
Avatar
Lin Wang
3 views
Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling

Advanced models of lobular breast cancer metas...

Cancer Biology
Avatar
librarian
3 views
Load more