Cancer Biology

Elongin B orchestrates chromatin and transcriptional programs in H3K27M-mutant diffuse midline glioma

Elongin B orchestrates chromatin and transcrip...

Cancer Biology
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librarian
3 views
Tumoral Switch in NUMB splicing changes essential transcription pathways and induces malignant properties in tumour cells

Tumoral Switch in NUMB splicing changes essent...

Cancer Biology
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librarian
3 views
β-Hydroxybutyrate elicits divergent metabolic responses between MCF-7 and T47D ER+ breast cancer cells under glucose restriction

β-Hydroxybutyrate elicits divergent metabolic ...

Cancer Biology
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Michael Weichhaus
5 views
MYC overexpression drives poor prognosis and differential sensitivity to treatments according to TP53 status in chronic lymphocytic leukemia

MYC overexpression drives poor prognosis and d...

Cancer Biology
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María Hernández-Sánchez
6 views
Cellular stemness identifies high-risk ductal carcinoma in situ and offers a therapeutic interception opportunity

Cellular stemness identifies high-risk ductal ...

Cancer Biology
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librarian
19 views
Neutral Sphingomyelinase-2 Restrains TAZ to Suppress Breast Tumor Growth

Neutral Sphingomyelinase-2 Restrains TAZ to Su...

Cancer Biology
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librarian
14 views
LVV SMRTcap reveals extensive proviral variation in lentiviral vector-transduced CAR T cells

LVV SMRTcap reveals extensive proviral variati...

Cancer Biology
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librarian
11 views
Genomic, Clinical, and Spatial Predictors of Durable Response to BRAF/MEK Inhibition in BRAF-Mutant Melanoma

Genomic, Clinical, and Spatial Predictors of D...

Cancer Biology
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librarian
10 views
Purinergic signaling promotes gliomagenesis through nuclear calcium transients

Purinergic signaling promotes gliomagenesis th...

Cancer Biology
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librarian
9 views
Glutamatergic neuron-tumor synapses shape human glioblastoma cell states through radial glia plasticity

Glutamatergic neuron-tumor synapses shape huma...

Cancer Biology
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librarian
10 views
Cell line-dependent effects of spheroid formation method on drug response in melanoma models

Cell line-dependent effects of spheroid format...

Cancer Biology
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Akvilė Žilytė
11 views
Integrated spatial and single-cell transcriptomic analysis of aggressive glioblastoma growth dynamics.

Integrated spatial and single-cell transcripto...

Cancer Biology
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librarian
17 views
Compact serum miRNA qPCR model for pancreatic cancer discrimination with independent and clinical validation

Compact serum miRNA qPCR model for pancreatic ...

Cancer Biology
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Yoshitake Sano
18 views
FASN Inhibition Resensitizes Chordoma to Radiotherapy by Targeting Adaptive Unsaturated Fatty Acid Metabolism

FASN Inhibition Resensitizes Chordoma to Radio...

Cancer Biology
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librarian
14 views
Integrated Collagen Architecture and Composition Improve Risk Stratification in Triple-Negative Breast Cancer

Integrated Collagen Architecture and Compositi...

Cancer Biology
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librarian
14 views
Functional T cells trapped behind a stromal wall: a Brake-with-Wall phenotype redefines pancreatic adenocarcinoma immunotherapy resistance

Functional T cells trapped behind a stromal wa...

Cancer Biology
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Jeong-Soon Yong
11 views
The miR-221-5p/RAD18/RAD51 axis regulates DNA damage tolerance and homologous recombination to drive platinum resistance in ovarian cancer.

The miR-221-5p/RAD18/RAD51 axis regulates DNA ...

Cancer Biology
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Komaraiah Palle
13 views
The CNS-penetrant MAP4K inhibitor famlasertib restrains medulloblastoma dissemination without developmental toxicity

The CNS-penetrant MAP4K inhibitor famlasertib ...

Cancer Biology
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librarian
12 views
Ablation of glypican-3 enhances radiosensitivity in liver cancer by prolonging G2/M arrest and activating the ATM/CHK2 pathway

Ablation of glypican-3 enhances radiosensitivi...

Cancer Biology
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Joon-Yong Chung
47 views
Profilin-1 Promotes Chromophobe Renal Cell Carcinoma Malignancy

Profilin-1 Promotes Chromophobe Renal Cell Car...

Cancer Biology
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librarian
13 views
TumorArchetypeR: A modular framework to derive signature-based tumor subtypes

TumorArchetypeR: A modular framework to derive...

Cancer Biology
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librarian
11 views
Collective cancer cell calcium activity drives brain metastasis

Collective cancer cell calcium activity drives...

Cancer Biology
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librarian
14 views
Neuroendocrine-like/EMT dedifferentiation mediates resistance to EGFR inhibitors via the NRG1/HER3 axis

Neuroendocrine-like/EMT dedifferentiation medi...

Cancer Biology
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Mattia Lauriola
15 views
SOCS1 expression in prostate epithelial cells is essential for tissue homeostasis and tumor suppression

SOCS1 expression in prostate epithelial cells ...

Cancer Biology
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librarian
20 views
Inhibition of the Adenosine pathway activates the immune response against Mesothelioma.

Inhibition of the Adenosine pathway activates ...

Cancer Biology
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Brittany Magalis
18 views
Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14

Astrocyte immunosuppressive activity in gliobl...

Cancer Biology
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librarian
13 views
A computational model reveals that spatial localization of cancer stem cells increases radioresistance in tumorspheres

A computational model reveals that spatial loc...

Cancer Biology
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librarian
25 views
Efficacy evaluation of glasedgib Sonic Hedgehog pathway inhibition with or without inotuzumab in B-ALL cells using a new co-culturing system model and a validated chemosensitivity assay

Efficacy evaluation of glasedgib Sonic Hedgeho...

Cancer Biology
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Cecilia Yeung
16 views
Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas

Targeting an RNA Editor to Impede H3K27M+ Pedi...

Cancer Biology
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librarian
22 views
Machine Learning Analysis to Define Cell Lineage in Leiomyosarcoma

Machine Learning Analysis to Define Cell Linea...

Cancer Biology
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librarian
19 views
Tumor-associated tissue-resident macrophages drive pancreatic cancer progression through IGF1-IGF1R signaling

Tumor-associated tissue-resident macrophages d...

Cancer Biology
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Naoki Tanimizu
16 views
Antibody Blockade of Ly49/MHC-I interactions enhances Innate and Adaptive Immunity Against Cancer Metastasis

Antibody Blockade of Ly49/MHC-I interactions e...

Cancer Biology
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librarian
19 views
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