Cancer Biology

Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian cancer

Matrix structure and microenvironment dynamics...

Cancer Biology
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Frances Balkwill
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Patient-Derived Three-Dimensional Lung Tumor Models to Evaluate Response to Immunotherapy

Patient-Derived Three-Dimensional Lung Tumor M...

Cancer Biology
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Kayla Goliwas
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Determining preclinical safety of Aclarubicin in pediatric malignancies

Determining preclinical safety of Aclarubicin ...

Cancer Biology
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librarian
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SMARCA4 is essential for early-stage tumor development but its loss promotes late-stage cancer progression in small-cell lung cancer

SMARCA4 is essential for early-stage tumor dev...

Cancer Biology
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Kwon-Sik Park
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Therapy resistance in AML is mediated by cytoplasmic sequestration of the transcriptional repressor IRF2BP2

Therapy resistance in AML is mediated by cytop...

Cancer Biology
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librarian
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PIWIL2 downregulation in colon cancer promotes transposon activity and pro-tumorigenic phenotypes

PIWIL2 downregulation in colon cancer promotes...

Cancer Biology
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librarian
1 view
The epigenetic regulator TRIM24 controls melanoma cell dedifferentiation and resistance to treatment in melanoma

The epigenetic regulator TRIM24 controls melan...

Cancer Biology
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Julie Caramel
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In silico drug sensitivity predicts subgroup-specific therapeutics in medulloblastoma patients

In silico drug sensitivity predicts subgroup-s...

Cancer Biology
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librarian
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Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG

Integrative Multi-Omics Analysis Identifies Nu...

Cancer Biology
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librarian
4 views
The 1p/19q co-deletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas

The 1p/19q co-deletion induces targetable and ...

Cancer Biology
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librarian
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Optimisation of pembrolizumab therapy for de novo metastatic MSI-H/dMMR colorectal cancer using data-driven delay integro-differential equations

Optimisation of pembrolizumab therapy for de n...

Cancer Biology
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librarian
1 view
Predicting GD2 expression across cancer types by the integration of pathway topology and transcriptome data

Predicting GD2 expression across cancer types ...

Cancer Biology
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Arsenij Ustjanzew
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PLK1-mediated phosphorylation of PHGDH reprograms serine metabolism in advanced prostate cancer

PLK1-mediated phosphorylation of PHGDH reprogr...

Cancer Biology
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librarian
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Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal Adenocarcinoma

Spatial Biology and Organoid Technologies Reve...

Cancer Biology
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librarian
3 views
Deficiencies in the Fanconi Anemia or the Homologous Recombination Pathway enhance the antitumor effects of the novel hypoxia-activated prodrug CP-506

Deficiencies in the Fanconi Anemia or the Homo...

Cancer Biology
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librarian
1 view
Contrastive Representation Learning for Single Cell Phenotyping in Whole Slide Imaging of Enrichment-free Liquid Biopsy

Contrastive Representation Learning for Single...

Cancer Biology
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librarian
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Feeding induces c-Fos in hepatocytes contributing to hepatocellular carcinoma in obesity

Feeding induces c-Fos in hepatocytes contribut...

Cancer Biology
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librarian
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In vivo anti-tumor activity of high-dose parenteral ascorbic acid is mediated primarily via cofactor activity, not via oxidative stress.

In vivo anti-tumor activity of high-dose paren...

Cancer Biology
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librarian
1 view
Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation

Aperiodic neural dynamics define a novel signa...

Cancer Biology
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Shawn Hervey-Jumper
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A New Class of Precision Therapeutics that Inhibit Prostate Cancer Mediated Bone Destruction

A New Class of Precision Therapeutics that Inh...

Cancer Biology
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librarian
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Repurposing Romidepsin for Osteosarcoma: Screening FDA-Approved Oncology Drugs with Three-Dimensional Osteosarcoma Spheroids

Repurposing Romidepsin for Osteosarcoma: Scree...

Cancer Biology
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Edward Greenfield
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Circulating Biomarkers for Therapeutic Response to Immune Checkpoint Inhibitor Therapy in Patients with Advanced Lung Cancer

Circulating Biomarkers for Therapeutic Respons...

Cancer Biology
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Jaswinder Singh Maras
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An oncolytic herpesvirus expressing a CXCR4 antagonist interferes with Glioblastoma cells stemness features and migration.

An oncolytic herpesvirus expressing a CXCR4 an...

Cancer Biology
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Catherine SADZOT-DELVAUX
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Development of Paclitaxel Resistance in Triple-Negative Breast Cancer Is Associated with Extensive DNA Methylation Changes That Are Partially Reversed by Decitabine

Development of Paclitaxel Resistance in Triple...

Cancer Biology
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Bozena Smolkova
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Site-Specific Immune and Stromal Architecture Drive Resistance to Trastuzumab Deruxtecan in HER2+ Metastatic Breast Cancer

Site-Specific Immune and Stromal Architecture ...

Cancer Biology
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librarian
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IL-17A potentiates malignant T-cell viability via electron transport chain complex I in cutaneous T-cell lymphoma

IL-17A potentiates malignant T-cell viability ...

Cancer Biology
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Rahul Purwar
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Primary CD34+ cells of patients with VEXAS syndrome are highly sensitive to targeted treatment with TAK-243 and pevonedistat

Primary CD34+ cells of patients with VEXAS syn...

Cancer Biology
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Nanni Schmitt
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DNA2 and FANCM function in two distinctive pathways in disrupting TERRA R-loops and suppressing replication stress at ALT telomeres

DNA2 and FANCM function in two distinctive pat...

Cancer Biology
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librarian
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Identification and Characterization of PLUTO-201, a Novel Long Non-Coding RNA Associated with Poor Outcomes in Prostate Cancer

Identification and Characterization of PLUTO-2...

Cancer Biology
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Haolong Li
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Inflammation-induced endothelial cell activation and angiogenic sprouting are downmodulated by ubiquitin-specific peptidase 20

Inflammation-induced endothelial cell activati...

Cancer Biology
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Sudha Shenoy
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A First-in-Class Therapy Targeting Transcription-Replication Conflicts Drives Synthetic Lethality in Homologous Recombination Deficient Cancers

A First-in-Class Therapy Targeting Transcripti...

Cancer Biology
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librarian
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Overcoming treatment resistance mediated by the bone marrow vascular niche in acute myeloid leukemia

Overcoming treatment resistance mediated by th...

Cancer Biology
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librarian
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