Structural bases for Nuclear Factor 1-X activation and DNA recognition. Prototypic insight into the NFI transcription factor family

Structural bases for Nuclear Factor 1-X activa...

Biochemistry
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Marco Nardini
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Nucleotide and metalloid-driven conformational changes in the arsenite efflux ATPase ArsA

Nucleotide and metalloid-driven conformational...

Biochemistry
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Douglas Rees
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AI-assisted isolation of bioactive Dipyrimicins from Amycolatopsis azurea and identification of its corresponding dip biosynthetic gene cluster

AI-assisted isolation of bioactive Dipyrimicin...

Biochemistry
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librarian
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Optimizing PDIA1 Inhibition as a Strategy to Inhibit NLRP3 Inflammasome Activation and Activity

Optimizing PDIA1 Inhibition as a Strategy to I...

Biochemistry
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librarian
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The individual isoforms of ORMDL, the regulatory subunit of serine palmitoyltransferase, have distinctive sensitivities to ceramide.

The individual isoforms of ORMDL, the regulato...

Biochemistry
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librarian
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Metal ion requirement for catalysis by 3'-5' RNA polymerases

Metal ion requirement for catalysis by 3'-5' R...

Biochemistry
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librarian
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The bacterial chaperone CsgC inhibits functional amyloid CsgA formation by promoting the intrinsically disordered pre-nuclear state

The bacterial chaperone CsgC inhibits function...

Biochemistry
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Matthew Chapman
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It runs in the family: Discovery of enzymes in the oleuropein pathway in Olive (Olea europaea) by comparative transcriptomics

It runs in the family: Discovery of enzymes in...

Biochemistry
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librarian
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High Glucose Diet Induces Hepatic Iron Overload Contributing to Metabolic Dysfunction

High Glucose Diet Induces Hepatic Iron Overloa...

Biochemistry
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Marie Heffern
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A novel screening assay for insulin receptor

A novel screening assay for insulin receptor

Biochemistry
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librarian
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Artesunate Alleviate Kidney Fibrosis by Restoring Klotho Protein and Suppressing Wnt/β-Catenin Signalling Pathway

Artesunate Alleviate Kidney Fibrosis by Restor...

Biochemistry
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Goran Mohammad
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Sorted-Cell Proteomics Reveals an AT1-Associated Epithelial Cornification Phenotype and Suggests Endothelial Redox Imbalance in Human Bronchopulmonary Dysplasia

Sorted-Cell Proteomics Reveals an AT1-Associat...

Biochemistry
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librarian
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Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release

Biophysical characterization of Eag chaperones...

Biochemistry
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librarian
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Live-cell NanoBRET assay to measure AKT inhibitor binding to conformational states of AKT

Live-cell NanoBRET assay to measure AKT inhibi...

Biochemistry
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librarian
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Midkine Attenuates Aβ Fibril Assembly and Amyloid Plaque Formation

Midkine Attenuates Aβ Fibril Assembly and Amyl...

Biochemistry
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Yang Yang
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Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target

Natural product-mediated reaction hijacking me...

Biochemistry
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Amit Sharma
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Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation

Seal milk oligosaccharides rival human milk co...

Biochemistry
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librarian
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Functional Spectrum of USP7 Pathogenic Variants in Hao-Fountain Syndrome: Insights into the Enzyme's Activity, Stability, and Allosteric Modulation

Functional Spectrum of USP7 Pathogenic Variant...

Biochemistry
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librarian
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Hydrogen-Induced Calcium Influx via the TRPC4-TRPC4AP Axis

Hydrogen-Induced Calcium Influx via the TRPC4-...

Biochemistry
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Xuemei Ma
41 views
A study of different pre-treatment methods for cigarettes and their aroma differences

A study of different pre-treatment methods for...

Biochemistry
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librarian
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Ubiquilin-2 liquid droplets catalyze α-synuclein fibril formation

Ubiquilin-2 liquid droplets catalyze α-synucle...

Biochemistry
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librarian
2 views
ATP hydrolysis-driven structural transitions within the S. cerevisiae Rad51 and Dmc1 nucleoprotein filaments

ATP hydrolysis-driven structural transitions w...

Biochemistry
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Eric Greene
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Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers

Towards a unified molecular mechanism for liga...

Biochemistry
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librarian
3 views
An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents

An unbiased cell-culture selection yields DNA ...

Biochemistry
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librarian
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Discovery of a VHL molecular glue degrader of GEMIN3 by Picowell RNA-seq

Discovery of a VHL molecular glue degrader of ...

Biochemistry
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Patrick Ryan Pots
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Nonenzymatic RNA copying with a potentially primordial genetic alphabet

Nonenzymatic RNA copying with a potentially pr...

Biochemistry
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librarian
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State-of-the-art covalent virtual screening with AlphaFold3

State-of-the-art covalent virtual screening wi...

Biochemistry
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librarian
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High-resolution NMR spectroscopy of proteins in intact mitochondria

High-resolution NMR spectroscopy of proteins i...

Biochemistry
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Conggang Li
1 view
Dissecting a biological electron transport network with electrochemistry

Dissecting a biological electron transport net...

Biochemistry
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librarian
1 view
Revealing the unexpected interplay between the Proteasome Activator PA200 and the immunoproteasome

Revealing the unexpected interplay between the...

Biochemistry
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librarian
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Identification of novel human topoisomerase III beta inhibitors

Identification of novel human topoisomerase II...

Biochemistry
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Yasir Mamun
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New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands and transcriptional coregulators

New structural insights into the control of th...

Biochemistry
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Albane le Maire
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